Karo's Characteristics
Karo's mysticism was not speculative in nature; and he devoted time to the Kabbalah, his maggid often exhorted him not to neglect the study of it (Maggid Mesharim, p. 57b). The catastrophe that came upon the Pyrenean Jews made such an impression upon the minds of the best among them that many saw therein the signs of Messianic travail, (compare Jacob Berab); and Karo, according to a contemporary, took this dark view throughout his life. While men like Molkho and David Reubeni were led to commit extravagant and foolish deeds under the influence of this idea. Berab's and Karo's nobility of nature came to the fore. If Karo indulged in mystical visions, and, half dreaming, thought he heard heavenly voices in his soul, they served always as reminders to him that his life, his actions, and his accomplishments must surpass those of other people (ib. Toledot, p. 9; Azharot, p. 3b, and passim).
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He died on the 13 Nisan 5335 (1575 CE) aged of 87.
Read more about this topic: Joseph Ben Ephraim Karo