John Ponsonby may refer to:
- John Ponsonby (politician) (1713–1789), Irish politician
- John Ponsonby, 1st Viscount Ponsonby (c.1772–1855), British diplomat
- John Ponsonby, 4th Earl of Bessborough (1781–1847), English politician
- John Ponsonby, 5th Earl of Bessborough (1809–1880), British politician
- John Ponsonby (British Army officer) (1866-1952), British general
- John Ponsonby (RAF officer), senior commander in the Royal Air Force