Other
- John O'Neill (VC) (1897–1942), Scottish recipient of the Victoria Cross during the First World War
- John Joseph O'Neill (journalist) (1889–1953), winner of the Pulitzer Prizer for Reporting
- John P. O'Neill (1952–2001), former FBI agent and head of security at the World Trade Center at the time of the September 11, 2001 attacks
- John O'Neill (editor), founding editor of Black Gate magazine
- John O'Neill (poet) (1777–1854), Irish writer, poet and playwright
- John O'Neill (architect), oversaw the completion of St Peter's Cathedral, Belfast
- John O'Neill, 3rd Earl of Tyrone (died 1641), the son of Hugh O'Neill
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