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- John Babbacombe Lee (1864–1941), convicted English murderer noted for surviving three attempts to hang him
- General John C. H. Lee (1887–1958), deputy commander of U.S. forces in Europe in World War II
- John D. Lee (1812–1877), Mormon leader
- John Lee (inventor), Scottish-Canadian inventor and arms designer
- John Black Lee, modern architect in New Canaan, Connecticut
- John Milton Lee (1890–1958), founder of Kappa Alpha Psi Fraternity
- John Z. Lee (born 1968), Chicago attorney and judicial nominee
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