John Casimir may refer to:
- John II Casimir of Poland (1609–1672)
- Johann Casimir of Simmern (1543–1592)
- John Casimir, Duke of Saxe-Coburg (1564–1633)
- John Casimir (clarinetist) (1898–1963)
- John Casimir, Count Palatine of Kleeburg (1589–1652), father of Karl X Gustav of Sweden
- John Casimir Ehrnrooth, Finnish soldier
- John Casimir Zichy Woinarski, Australian ornithologist
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