James Duffy may refer to:
- James E. Duffy, Jr. (born 1942), retired associate justice of the Hawaii State Supreme Court
- James Duffy (psychiatrist), neuropsychiatrist and associate professor of clinical psychiatry at the University of Connecticut
- James Duffy (Irish publisher) (1809–1871), Irish publisher of Nationalist and Roman Catholic books, bibles and religious texts
- James Duffy (athlete) (1890–1915), winner of the 1914 Boston Marathon
- James Duffy (VC) (1889–1969), Irish recipient of the Victoria Cross in 1917
- James Duffy, a character in the short story "A Painful Case" (part of the book Dubliners) by James Joyce
- James Duffy (cricketer)
- James Albert Duffy (died 1968), first bishop for the Diocese of Grand Island
- James F. Duffy, American football coach
- James P.B. Duffy (1878–1969), former U.S. Congressman from New York
- Jamie Duffy (born 1983), Irish footballer
- Jim Duffy (journalist) (born 1966), journalist, political commentator, and Irish advisor to Australia's Republic Advisory Committee
- Jim Duffy (footballer) (born 1959), former caretaker manager of Norwich City F.C.
- Jim Duffy (rugby league), rugby league footballer
- Jim Duffy (journalist) (born 1966), Irish historian and political commentator
- Jim Duffy (umpire) (1920–2003), American baseball umpire
- Jim Duffy (animator) (died 2012), American animator
Famous quotes containing the word james:
“It was a real treat when he’d read me Daisy Miller out loud. But we’d reached the point in our relationship when, in a straight choice between him and Henry James, I’d have taken Henry James any day even if Henry James were dead and not much of a one for the girls when living, either.”
—Angela Carter (1940–1992)