Jacobus Henricus Van 't Hoff - Career

Career

Before he received his doctorate, van 't Hoff had already published the first of his important contributions to the field of organic chemistry. In 1874 he accounted for the phenomenon of optical activity by assuming that the chemical bonds between carbon atoms and their neighbors were directed towards the corners of a regular tetrahedron. This three-dimensional structure accounted for the isomers found in nature. He shares credit for this with the French chemist Joseph Le Bel, who independently came up with the same idea.

Van 't Hoff published his work on stereochemistry in his book La chimie dans l'espace in 1874. At the time, his theory was considered revolutionary and was strongly criticized by the scientific community. One such critic was the renowned editor of the German Journal für praktische Chemie, Adolph Kolbe, who stated:

"A Dr. H. van ’t Hoff of the Veterinary School at Utrecht has no liking, apparently, for exact chemical investigation. He has considered it more comfortable to mount Pegasus (apparently borrowed from the Veterinary School) and to proclaim in his ‘La chimie dans l’espace’ how the atoms appear to him to be arranged in space, when he is on the chemical Mt. Parnassus which he has reached by bold flight."

In 1884, van 't Hoff published his research on chemical kinetics, titled Études de Dynamique chimique ("Studies in Chemical Dynamics"), in which he described a new method for determining the order of a reaction using graphics, and applied the laws of thermodynamics to chemical equilibria. He also introduced the modern concept of chemical affinity. In 1886, he showed a similarity between the behaviour of dilute solutions and gases. In 1887, he and German chemist Wilhelm Ostwald founded an influential scientific magazine named Zeitschrift für physikalische Chemie ("Journal of Physical Chemistry"). He worked on Svante Arrhenius's theory of the dissociation of electrolytes and in 1889 provided physical justification for the Arrhenius equation. In 1896, he became a professor at the Prussian Academy of Science in Berlin. His studies of the salt deposits at Stassfurt were an important contribution to Prussia's chemical industry.

Van 't Hoff became a lecturer in chemistry and physics at the Veterinary College in Utrecht. He then worked as a professor of chemistry, mineralogy, and geology at the University of Amsterdam for almost 18 years before eventually becoming the chairman of the chemistry department. In 1896 van 't Hoff moved to Germany where he finished his career at the University of Berlin in 1911. In 1901 he received the first Nobel Prize in chemistry for his work with solutions. His work showed that very dilute solutions follow mathematical laws that closely resemble the laws describing the behavior of gases.