Genetics
The disorder has an autosomal recessive inheritance pattern, which means the defective gene is located on an autosome, and two copies of the gene - one from each parent - must be inherited to be affected by the disorder. The parents of a child with an autosomal recessive disorder are carriers of one copy of the defective gene, but are usually not affected by the disorder.
Mutations in both copies of the IVD gene result in isovaleric acidemia.
Read more about this topic: Isovaleric Acidemia