Interstate 81 - Major Intersections

Major Intersections

• Interstate 40 near Dandridge, Tennessee, northeast of Knoxville, TN.
• Interstate 26 between the Tri-Cities.
• Interstate 77 in Wytheville, VA. They stay joined for about 10 miles (16 km), and go in opposite directions (i.e., this is a wrong-way concurrency, where I-81 North overlaps I-77 South, and vice versa).
• Interstate 64 in Lexington, VA. They stay joined through Staunton, VA.
• Interstate 66 in Middletown, VA
• Interstate 70 in Hagerstown, MD.
• Interstate 76/Pennsylvania Turnpike (via U.S. Route 11) in Middlesex Township, PA (near Carlisle, PA).
• Interstate 83 in Harrisburg, PA
• Interstate 78 near Jonestown, PA.
• Interstate 80 near Hazleton, PA.
• Interstate 476/PA Tpk NE Ext. in Dupont, Pennsylvania (near Pittston, PA).
• Interstate 84 and Interstate 380 in Dunmore, Pa. (near Scranton, PA). Throop Dunmore Interchange.
• Interstate 476/PA Tpk NE Ext.(again) in Clarks Summit, PA.
• 
  Future Interstate 86/NY 17 in Binghamton, NY.
• Interstate 88 in Binghamton, NY.
• I-690 in downtown Syracuse, NY.
• Interstate 90/New York State Thruway in North Syracuse, NY.