Influenza A Virus Subtype H5N2 - H5N2 and Humans

H5N2 and Humans

Japan's Health Ministry said in January, 2006 that poultry farm workers in Ibaraki prefecture may have been exposed to H5N2 (which was not previously known to infect humans) in 2005. Data were collected from 257 workers at 35 chicken farms by Ibaraki prefectural government. Using a Wilcoxon signed-rank test, it was determined that the H5N2 antibody titers of the second samples of paired sera were significantly higher than those of the first samples (p<0.001). The H5N2 antibody titers of paired sera of 13 subjects increased fourfold or more. The results suggest that this may have been the first avian influenza H5N2 infection from poultry to affect humans.

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