Treatment
Multimodal therapy including chemotherapy with a combination of several agents, radiation therapy, hormonal therapy where appropriate and in some cases surgery.
Estrogen antagonist or aromatase inhibitors appear to improve outcome for ER positive cancer, similar for Herceptin.
Surgery was only rarely performed because inflammatory breast cancer is considered essentially a systemic cancer, however it may improve outcome and is now being reconsidered. A lumpectomy, when only a portion of the breast is removed, is not an option for IBC patients. A lymph node dissection is also recommended over a sentinel lymph node biopsy. Lymphedema, swelling of the arm and the hand on the side of the body where surgery was performed, may be a complication after a lymph node dissection. Reconstruction of the breast may be an option for healthy women after a mastectomy. However, for patients who smoke or have diabetes, complications are more common.
A number of promising new therapeutic agents exists, such as
- lapatinib - a Her2neu receptor antagonist
- various VEGF receptor antagonists
- tipifarnib - a farnesyltransferase inhibitor
Read more about this topic: Inflammatory Breast Cancer
Famous quotes containing the word treatment:
“If the study of all these sciences, which we have enumerated, should ever bring us to their mutual association and relationship, and teach us the nature of the ties which bind them together, I believe that the diligent treatment of them will forward the objects which we have in view, and that the labor, which otherwise would be fruitless, will be well bestowed.”
—Plato (c. 427–347 B.C.)
“I am glad you agree with me as to the treatment of the mining riots. We shall crush out the lawbreakers if the courts and juries do not fail.”
—Rutherford Birchard Hayes (1822–1893)
“Our treatment of both older people and children reflects the value we place on independence and autonomy. We do our best to make our children independent from birth. We leave them all alone in rooms with the lights out and tell them, “Go to sleep by yourselves.” And the old people we respect most are the ones who will fight for their independence, who would sooner starve to death than ask for help.”
—Margaret Mead (1901–1978)