Infant respiratory distress syndrome (IRDS), also called neonatal respiratory distress syndrome or respiratory distress syndrome of newborn, previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of surfactant production and structural immaturity in the lungs. It can also result from a genetic problem with the production of surfactant associated proteins. IRDS affects about 1% of newborn infants and is the leading cause of death in preterm infants. The incidence decreases with advancing gestational age, from about 50% in babies born at 26–28 weeks, to about 25% at 30–31 weeks. The syndrome is more frequent in infants of diabetic mothers and in the second born of premature twins.
IRDS is distinct from pulmonary hypoplasia, another leading cause of neonatal death that involves respiratory distress.
Read more about Infant Respiratory Distress Syndrome: Clinical Course, Histopathology, Pathophysiology, Prevention, Treatment, Related Disorders, Famous Victims
Famous quotes containing the words infant, distress and/or syndrome:
“The colicky baby who becomes calm, the quiet infant who throws temper tantrums at two, the wild child at four who becomes serious and studious at six all seem to surprise their parents. It is difficult to let go of one’s image of a child, say goodbye to the child a parent knows, and get accustomed to this slightly new child inhabiting the known child’s body.”
—Ellen Galinsky (20th century)
“He is not affected by the reality of distress touching his heart, but by the showy resemblance of it striking his imagination. He pities the plumage, but forgets the dying bird.”
—Thomas Paine (1737–1809)
“[T]he syndrome known as life is too diffuse to admit of palliation. For every symptom that is eased, another is made worse. The horse leech’s daughter is a closed system. Her quantum of wantum cannot vary.”
—Samuel Beckett (1906–1989)