Example
If a fictional treatment costs a total of GBP 45,000 at today's value and increases a person's quality of life (QoL) from 0.5 to 0.6 for the remainder of their life from age 70 and onwards, and their expected lifespan increases from 73 to 75.
The total QALYs without the treatment are: 3 years * 0.5 = 1.5 QALYs
The total QALYs with the treatment are: 5 years * 0.6 = 3 QALYs
So the treatment is associated with a gain of 1.5 QALYs and a cost of GBP 45,000.
The ICER will then be GBP 45,000/1.5 = GBP 30,000 per QALY.
Read more about this topic: Incremental Cost-effectiveness Ratio
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