Idiopathic Short Stature - Definition

Definition

In 2003 Eli Lilly and Company offered a more precise definition of ISS when the pharmaceutical company submitted clinical trial data to the U.S. Food and Drug Administration (FDA) requesting approval to advertise their brand of growth hormone for the treatment of ISS. They proposed a definition of a height more than 2.25 standard deviations below mean, roughly equal to the shortest 1.2% of the population.

Other researchers have described a cutoff of 2.0 standard deviations.

Read more about this topic:  Idiopathic Short Stature

Famous quotes containing the word definition:

    “The man who knows governments most completely is he who troubles himself least about a definition which shall give their essence. Enjoying an intimate acquaintance with all their particularities in turn, he would naturally regard an abstract conception in which these were unified as a thing more misleading than enlightening.”
    —William James (1842–1910)

    “I’m beginning to think that the proper definition of “Man” is “an animal that writes letters.””
    —Lewis Carroll [Charles Lutwidge Dodgson] (1832–1898)

    “It’s a rare parent who can see his or her child clearly and objectively. At a school board meeting I attended . . . the only definition of a gifted child on which everyone in the audience could agree was “mine.””
    —Jane Adams (20th century)