Breadth of The Hypothesis
The hygiene hypothesis has expanded from eczema and hay fever to include exposure to several varieties of microorganisms and parasites, with which humans coexisted throughout much of our evolutionary history, as necessary for balanced and regulated immune system development. In recent times, the development of hygienic practices, elimination of childhood diseases, widespread use of antibiotics, and relative availability of effective medical care have diminished or eliminated exposure to these microorganisms and parasites during development. Examples of organisms that may be important for proper development of T regulatory cells include lactobacilli, various mycobacteria, and certain helminths.
Read more about this topic: Hygiene Hypothesis
Famous quotes containing the words breadth of, breadth and/or hypothesis:
“Fogs and clouds which conceal the overshadowing mountains lend the breadth of the plains to mountain vales. Even the small-featured country acquires some grandeur in stormy weather when clouds are seen drifting between the beholder and the neighboring hills.”
—Henry David Thoreau (1817–1862)
“After that came commencement day—that great day for which all other days were made. And it went. And that night I felt of myself all over, and to my astonishment, I found ‘twas the same old Rud. Not a single cubit added to my stature; not a hair’s breadth to my girth. If anything, on the contrary, I felt more lank and gaunt than common, much as if a load were off my stomach.”
—Rutherford Birchard Hayes (1822–1893)
“The hypothesis I wish to advance is that ... the language of morality is in ... grave disorder.... What we possess, if this is true, are the fragments of a conceptual scheme, parts of which now lack those contexts from which their significance derived. We possess indeed simulacra of morality, we continue to use many of the key expressions. But we have—very largely if not entirely—lost our comprehension, both theoretical and practical, of morality.”
—Alasdair Chalmers MacIntyre (b. 1929)