Hydroxysteroid Dehydrogenase

The Hydroxysteroid dehydrogenases are a group of alcohol oxidoreductases that catalyze the dehydrogenation of hydroxysteroids.

There are four types, classified by the number of the carbon acted upon:

Carbon From To
3 pregnenolone progesterone
3 17-Hydroxypregnenolone 17-Hydroxyprogesterone
3 dehydroepiandrosterone androstenedione
11 cortisol cortisone
17 androstenedione testosterone
20 progesterone 20-alpha-dihydroprogesterone