Users
- Albania: Garda e Republikes.
- Argentina
- Australia: Royal Australian Air Force Airfield Defence Guards, Special Operations Command, and all Police Tactical Groups.
- Austria: EKO Cobra.
- Bahrain
- Bangladesh: Army, Special Forces, Rapid Action Battalion, and Bangladesh Navy Special Warfare Diving And Salvage.
- Belgium
- Bulgaria: 160 imported in 2009.
- Cameroon
- Canada: Canadian Forces Naval Boarding Party, and Royal Canadian Mounted Police.
- Chile
- China: Used by Chongqing SWAT (NR-08, Chinese copy of MP5)
- Costa Rica: UEA (Unidad Especial de Apoyo) Special Police Unit.
- Croatia: Lučko Anti-Terrorist Unit
- Czech Republic: URNA counter-terrorist group and other units of the armed forces (MP5A5, MP5SD6, MP5K-PDW).
- Democratic Republic of Congo
- Denmark
- Ecuador: Special units GOE (Grupo de Operaciones Especiales) and GIR (Grupo de Intervención y Rescate) from the National Police.
- El Salvador
- Estonia:Estonian Police.
- Finland: Finnish Defence Forces under designation 9.00 konepistooli 2000.
- France: GIGN and certain specialized units within the French Army.
- Georgia: MP5K and MP5SD.
- Germany: Bundespolizei (Federal Police), Landespolizei (State Police), German Army, Feldjäger (Military Police), GSG 9 special operations unit and German Navy.
- Ghana
- Greece: Manufactured locally by Hellenic Defence Systems (EAS: Ellinika Amyntika Systimata). Used by the EKAM counter-terrorist group.
- Honduras
- Hong Kong: Hong Kong Police Force (used by Airport Security Unit, Counter Terrorism Response Unit, Emergency Unit, Police Tactical Unit, Small Boat Unit, Special Duties Unit, CIB Surveillance Support Unit, VIP Protection Unit, Witness Protection Unit, and other regular units with various models of original HK).
- Iceland: Víkingasveitin, Icelandic National Police.
- India: Indian Army, MARCOS, National Security Guards, and Maharashtra State Force One. Also used by the Special Protection Group until 2008, when it was replaced with the FN P90 and FN F2000.
- Indonesia: Komando Pasukan Katak (Kopaska) tactical diver group of Indonesian Navy, Komando Pasukan Khusus (Kopassus) special forces group of Indonesian Army,.
- Iran: Produced under license.
- Iraq
- Ireland: Irish Army Rangers.
- Italy: Used by the Carabinieri.
- Jamaica: Jamaica Constabulary Force.
- Japan: Special Boarding Unit(SBU) of Japanese Maritime Self-Defense Forces,Special Assault Team (SAT), Special Investigation Team (SIT), Martial Arts Attack Team (MAAT) of Japanese Police.
- Jordan
- Kuwait
- Kenya: Kenya Police.
- Republic of Korea: Republic of Korea Naval Special Warfare Brigade uses MP5A5 and MP5SD6.
- Liechtenstein: Special Police Unit, Security Corps.
- Lithuania: Lithuanian Armed Forces.
- Luxembourg: Unité Spéciale de la Police intervention unit of the Grand Ducal Police.
- Malaysia: Grup Gerak Khas, PASKAL and PASKAU, as well as the Pasukan Gerakan Khas.
- Malta: Armed Forces of Malta
- Mauritius
- Mexico: Manufactured under license.
- Netherlands: Dutch Royal and Diplomatic security (DKDB)
- New Zealand: New Zealand Special Air Service Commandos and New Zealand Police Special Tactics Group
- Nicaragua
- Niger
- Nigeria
- Norway: Norwegian Armed Forces, to be replaced by the MP7. Norwegian Police Service
- Pakistan: Pakistan Army, built by Pakistan Ordnance Factories.
- Philippines: Armed Forces of the Philippines, and Philippine National Police Special Action Force and other police and SWAT units.
- Poland: GROM special forces unit., FORMOZA special force unit, Police, Border Guard, CBA, ABW, Financial Police, Military Police Special Unit from Warsaw
- Portugal: Grupo de Operações Especiais (GOE).
- Qatar
- Romania: Land Forces Special Operations battalions.
- Saudi Arabia
- Serbia
- Singapore: Singapore Armed Forces Commando Formation and Singapore Police Force (replacing the Sterling submachine guns in the paramilitary units of Gurkha Contingent, Police Coast Guard, Police Special Operations Command and Special Tactics and Rescue Team (STAR)).
- Slovakia: Various police forces.
- Slovenia: Slovenian Armed Forces and Slovenian Police
- South Africa: Special Task Force.
- Spain: Grupo Especial de Operaciones (GEO).
- Sri Lanka
- Sudan: Manufactured by Military Industry Corporation as the Tihraga.
- Sweden: Swedish Police Service.
- Taiwan
- Thailand
- Turkey: Used by various services. Manufactured by MKEK.
- United Arab Emirates
- United Kingdom: Produced under license. Used by the United Kingdom Special Forces, Police Service of Northern Ireland, CO19, and most Authorised Firearms Officers. Semi-automatic version for routine police use.
- United States: Special Operations Forces, Secret Service, and FBI Hostage Rescue Team (10mm version). Also used by various police SWAT units at federal, state, and local levels.
- Uruguay
- Vatican City: Used by the Swiss Guard.
- Zambia
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