Haplogroup C (Y-DNA)

Haplogroup C (Y-DNA)

In human genetics, Haplogroup C is a Y-chromosome haplogroup, defined by UEPs M130/RPS4Y, M216, P184, P255, and P260, which are all SNP mutations. It is a sibling clade of Haplogroup F, within the more ancient grouping of Haplogroup CF. Unlike some other human Y-DNA clades of a similar age depth, all clades of Haplogroup CF are non-African; that is, they do not occur exclusively in Africa, unlike A and B. Haplogroup C-M130 in particular appears to be one of the Y-DNA clades which dispersed especially early towards the east; its phylogeographic distribution supports a single coastal Out-of-Africa route by way of the Indian subcontinent, which eventually led to the early settlement of modern humans in mainland Southeast Asia.