Severity
There are numerous different mutations which cause haemophilia A. Due to differences in changes to the gene involved (and the subsequent resulting protein), patients with haemophilia often have some level of active clotting factor. Individuals with less than 1% active factor are classified as having severe haemophilia, those with 1–5% active factor have moderate haemophilia, and those with mild haemophilia have between 5–40% of normal levels of active clotting factor.
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Famous quotes containing the word severity:
“When the severity of the law is to be softened, let pity, not bribes, be the motive.”
—Miguel De Cervantes (1547–1616)
“A Man who always acts in the Severity of Wisdom, or the Haughtiness of Quality, seems to move in a personated Part: It looks too Constrained and Theatrical for a Man to be always in that Character which distinguishes him from others.”
—Richard Steele (1672–1729)
“In compassionate men, severity is a virtue.”
—Friedrich Nietzsche (1844–1900)