A growth cone is a dynamic, actin-supported extension of a developing axon seeking its synaptic target. Their existence was originally proposed by Spanish histologist Santiago Ramón y Cajal based upon stationary images he observed under the microscope. He first described the growth cone based on fixed cells as “a concentration of protoplasm of conical form, endowed with amoeboid movements” (Cajal, 1890). Neuronal growth cones are situated on the very tips of nerve cells on structures called axons and dendrites. The sensory, motor, integrative, and adaptive functions of growing axons and dendrites are all contained within this specialized structure.
Read more about Growth Cone: Structure, Axon Branching and Outgrowth, Axon Guidance
Famous quotes containing the word growth:
“The windy springs and the blazing summers, one after another, had enriched and mellowed that flat tableland; all the human effort that had gone into it was coming back in long, sweeping lines of fertility. The changes seemed beautiful and harmonious to me; it was like watching the growth of a great man or of a great idea. I recognized every tree and sandbank and rugged draw. I found that I remembered the conformation of the land as one remembers the modelling of human faces.”
—Willa Cather (1873–1947)