Similarities With TCA Cycle
The glyoxylate cycle utilizes three of the five enzymes associated with the tricarboxylic acid cycle and shares many of its intermediate steps. The two cycles vary when, in the glyoxylate cycle, ICL converts isocitrate into glyoxylate and succinate instead of α-ketoglutarate as seen in the TCA cycle. This bypasses the decarboxylation steps that take place in the TCA cycle, allowing simple carbon compounds to be used in the later synthesis of macromolecules, including glucose. The glyoxylate cycle then continues on, using glyoxylate and acetyl-CoA to produce malate.
Read more about this topic: Glyoxylate Cycle
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