Glucose Tolerance Test - Interpretation of OGTT Results

Interpretation of OGTT Results

Fasting plasma glucose (measured before the OGTT begins) should be below 6.1 mmol/L (110 mg/dL). Fasting levels between 6.1 and 7.0 mmol/L (110 and 125 mg/dL) are borderline ("impaired fasting glycaemia"), and fasting levels repeatedly at or above 7.0 mmol/L (126 mg/dL) are diagnostic of diabetes.

The 2 hour OGTT glucose level should be below 7.8 mmol/L (140 mg/dL). Levels between this and 11.1 mmol/L (200 mg/dL) indicate "impaired glucose tolerance". Glucose levels above 11.1 mmol/L (200 mg/dL) at 2 hours confirms a diagnosis of diabetes.

1999 WHO Diabetes criteria - Interpretation of Oral Glucose Tolerance Test
Glucose levels NORMAL impaired fasting glycaemia (IFG) impaired glucose tolerance (IGT) Diabetes Mellitus (DM)
Venous Plasma Fasting 2hrs Fasting 2hrs Fasting 2hrs Fasting 2hrs
(mmol/L) <6.1 <7.8 > 6.1 & <7.0 <7.8 <7.0 >7.8 >7.0 >11.1
(mg/dL) <110 <140 >110 & <126 <140 <126 >140 >126 >200

Impaired glucose tolerance is often associated with insulin resistance and is often seen in Polycystic Ovary Syndrome.

Read more about this topic:  Glucose Tolerance Test

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