Related Enzymes: Notatin and Other Names
Notatin, extracted from antibacterial cultures of Penicillium notatum, was originally named Penicillin A, but was renamed to avoid confusion with penicillin. Notatin was shown to be identical to Penicillin B and glucose oxidase, enzymes extracted from other molds besides P. notatum; it is now generally known as glucose oxidase.
Early experiments showed that notatin exhibits in vitro antibacterial activity (in the presence of glucose) due to hydrogen peroxide formation. In vivo tests showed that notatin was not effective in protecting rodents from Streptococcus haemolyticus, Staphylococcus aureus, or salmonella, and caused severe tissue damage at some doses.
Read more about this topic: Glucose Oxidase
Famous quotes containing the words related and/or names:
“Perhaps it is nothingness which is real and our dream which is non-existent, but then we feel think that these musical phrases, and the notions related to the dream, are nothing too. We will die, but our hostages are the divine captives who will follow our chance. And death with them is somewhat less bitter, less inglorious, perhaps less probable.”
—Marcel Proust (1871–1922)
“There are names written in her immortal scroll at which Fame blushes!”
—William Hazlitt (1778–1830)