Globus Pallidus - Structure

Structure

Pallidal nuclei are made up of the same neuronal components. In primates, almost all pallidal neurons are very large, parvalbumin-positive, with very large dendritic arborizations. These have the peculiarity of having the three-dimensional shape of flat discs, parallel to one another, parallel to the border of the pallidum and perpendicular to the afferent striatopallidal axons. There are only a few small local circuitry neurons.

The globus pallidus is traversed by the numerous myelinated axons of the striato-pallidonigral bundle that give it the pale appearance from which it is named.

The ultrastructure is very peculiar, as the long dendrites are everywhere, without discontinuity, covered by synapses.

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