Gheorghe Cantacuzino may refer to several members of the Cantacuzino family:
- Gheorghe Grigore Cantacuzino, twice prime minister of Romania
- Gheorghe Cantacuzino (Ban of Craiova), Ban of Oltenia, son of Prince Şerban Cantacuzino
- Grigore Gheorghe Cantacuzino, mayor of Bucharest
- Gheorghe Cantacuzino-Grănicerul, soldier and fascist politician, see Corneliu Zelea Codreanu
- Gogu Cantacuzino, economist and government minister