Others
- George Smith (executioner) (1805–1874), English executioner also known as Throttler Smith
- George Smith (financier) (1808–1899), Chicago financier
- George Smith (horse) (born 1913), American Thoroughbred racehorse, 1916 Kentucky Derby winner
- George Smith (royal servant) (1960–2005), valet and footman to Charles, Prince of Wales
- George Smith (trade unionist) (died 1978), general secretary of UCATT
- George Allen Smith (1979–2005), missing cruise ship passenger
- George Bracewell Smith (1912–1976), London businessman and hotel owner
- George D. W. Smith (born 1943), materials scientist, co-invented the atom probe tomograph
- George E. Smith (born 1930), co-inventor of the charge-coupled device, received Nobel Prize in Physics
- George Edward Smith (born 1940), POW in Vietnam for 2 years, released in 1965
- George Girdler Smith (1795–1878), engraver in Boston, Massachusetts
- George Hugh Smith (1827–1901), Confederate Civil War veteran and prominent Los Angeles lawyer and judge
- George Joseph Smith (1872–1915), British "Brides in the Bath" murderer
- George Right Smith (1837–1903), Confederate soldier
- George Samuel Fereday Smith (1812–1891), English industrialist
- George Toogood Smith (1903–1955), uncle of Beatle John Lennon and husband of Mimi Smith
- George Smith (publisher) (1789–1846), Scottish born publisher
- George Smith (philanthropist) (1831–1895), campaigned against the use of industrial child labour
- George Smith (Hollyoaks), fictional character from British soap opera Hollyoaks
- George Smith (sports reporter), SportsCenter reporter
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