George Gaines may refer to:
- George Strother Gaines (1784–1873), American leader in the Mississippi Territory
- George Gaines (set decorator), Academy Award winner for Best Art Direction - Set Decoration
- George Gaynes, Finnish-born American actor (Police Academy)
Famous quotes containing the word george:
“I hope we may say that thus, this fateful morning, came to an end all wars.”
—David Lloyd George (1863–1945)