Gene Prediction - Combined Approaches

Combined Approaches

Programs such as Maker combine extrinsic and ab initio approaches by mapping protein and EST data to the genome to validate ab initio predictions. Augustus, which may be used as part of the Maker pipeline, can also incorporate hints in the form of EST alignments or protein profiles to increase the accuracy of the gene prediction.

Read more about this topic:  Gene Prediction

Famous quotes containing the words combined and/or approaches:

    “Thy knotted and combined locks to part,
    And each particular hair to stand on end,
    Like quills upon the fretful porpentine.”
    —William Shakespeare (1564–1616)

    “Bloody men are like bloody buses—
    You wait for about a year
    And as soon as one approaches your stop
    Two or three others appear.”
    —Wendy Cope (b. 1945)