Combined Approaches
Programs such as Maker combine extrinsic and ab initio approaches by mapping protein and EST data to the genome to validate ab initio predictions. Augustus, which may be used as part of the Maker pipeline, can also incorporate hints in the form of EST alignments or protein profiles to increase the accuracy of the gene prediction.
Read more about this topic: Gene Prediction
Famous quotes containing the words combined and/or approaches:
“The trick, which requires the combined skills of a tightrope walker and a cordon bleu chef frying a plain egg, is to take your [preteen] daughter seriously without taking everything she says and does every minute seriously.”
—Stella Chess (20th century)
“If I commit suicide, it will not be to destroy myself but to put myself back together again. Suicide will be for me only one means of violently reconquering myself, of brutally invading my being, of anticipating the unpredictable approaches of God. By suicide, I reintroduce my design in nature, I shall for the first time give things the shape of my will.”
—Antonin Artaud (1896–1948)