Combined Approaches
Programs such as Maker combine extrinsic and ab initio approaches by mapping protein and EST data to the genome to validate ab initio predictions. Augustus, which may be used as part of the Maker pipeline, can also incorporate hints in the form of EST alignments or protein profiles to increase the accuracy of the gene prediction.
Read more about this topic: Gene Prediction
Famous quotes containing the words combined and/or approaches:
“Riches have never fascinated me, unless combined with the greatest charm or distinction.”
—F. Scott Fitzgerald (1896–1940)
“These were not men, they were battlefields. And over them, like the sky, arched their sense of harmony, their sense of beauty and rest against which their misery and their struggles were an offence, to which their misery and their struggles were the only approaches they could make, of which their misery and their struggles were an integral part.”
—Rebecca West (1892–1983)