Finding Patterns Among Regulated Genes
Regulated genes are categorized in terms of what they are and what they do, important relationships between genes may emerge. For example, we might see evidence that a certain gene creates a protein to make an enzyme that activates a protein to turn on a second gene on our list. This second gene may be a transcription factor that regulates yet another gene from our list. Observing these links we may begin to suspect that they represent much more than chance associations in the results, and that they are all on our list because of an underlying biological process. On the other hand, it could be that if one selected genes at random, one might find many that seem to have something in common. In this sense, we need rigorous statistical procedures to test whether the emerging biological themes is significant or not. That is where gene set analysis comes in.
Read more about this topic: Gene Expression Profiling
Famous quotes containing the words finding, patterns, regulated and/or genes:
“To have no son, no wife,
No house or land still seemed quite natural.
Only a numbness registered the shock
Of finding out how much had gone of life,
How widely from the others.”
—Philip Larkin (1922–1986)
“Persons grouped around a fire or candle for warmth or light are less able to pursue independent thoughts, or even tasks, than people supplied with electric light. In the same way, the social and educational patterns latent in automation are those of self- employment and artistic autonomy.”
—Marshall McLuhan (1911–1980)
“Accidents will occur in the best regulated families; and in families not regulated by that pervading influence which sanctifies while it enhances the—a—I would say, in short, by the influence of Woman, in the lofty character of Wife, they may be expected with confidence, and must be borne with philosophy.”
—Charles Dickens (1812–1870)
“Whether you want it or not,
your genes have a political past,
your skin a political tone.
your eyes a political color.
...
you walk with political steps
on political ground.”
—Wislawa Szymborska (b. 1923)