Treatment
Treatment is usually debridement and excision with amputation necessary in many cases. Antibiotics alone are not effective because they do not penetrate ischaemic muscles enough to be effective. However, penicillin is given as an adjuvant treatment to surgery. In addition to surgery and antibiotics, hyperbaric oxygen therapy (HBOT) is used and acts to inhibit the growth of and kill the anaerobic C. perfringens.
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