Summary
Thus, GABAA receptors are ligand-gated ion channels, whereas GABAB receptors are G protein-coupled receptors.
This has a parallel to several other receptors in the body, in which a single molecule binds to receptors which function in completely different ways:
- acetylcholine binds to nicotinic and muscarinic acetylcholine receptors
- serotonin binds to 5-HT3 and metabotropic receptors
- glutamate binds to ionotropic and metabotropic receptors
- purines bind to ionotropic nucleotide-gated P2X and G protein-coupled P2Y receptors
Read more about this topic: GABA Receptor
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