G1 Phase - Restriction Point

Restriction Point

There is a "restriction point" present at the end of G1 phase. This point is a series of safeguards to ensure the DNA is intact and that the cell is functioning normally. Functionally, the safeguards exist as proteins known as cyclin-dependent kinases (CDK). The G1 CDK proteins activate the transcription factors for a variety of genes.These include genes which are responsible for DNA synthesis proteins and S phase CDK proteins.

Read more about this topic:  G1 Phase

Famous quotes containing the words restriction and/or point:

    “If we can find a principle to guide us in the handling of the child between nine and eighteen months, we can see that we need to allow enough opportunity for handling and investigation of objects to further intellectual development and just enough restriction required for family harmony and for the safety of the child.”
    —Selma H. Fraiberg (20th century)

    “Any historian of the literature of the modern age will take virtually for granted the adversary intention, the actually subversive intention, that characterizes modern writing—he will perceive its clear purpose of detaching the reader from the habits of thought and feeling that the larger culture imposes, of giving him a ground and a vantage point from which to judge and condemn, and perhaps revise, the culture that produces him.”
    —Lionel Trilling (1905–1975)