Frederick Campion Steward - Career

Career

A Rockefeller Foundation fellowship took him first to Cornell University in 1924 and then to the University of California at Berkeley four years later. In 1934 he returned to England as a Reader in botany and from 1940 to serve in the Ministry of Aircraft Production. After the war he returned to the USA, holding appointments at the Universities of Chicago and Rochester before finally moving to Cornell in 1950.

Ever fascinated by the unfolding processes of growth and development, Steward set out to study the behaviour of mature cells, isolated from carrot roots, when cultured in sterile nutrient culture media (liquid endosperm, or coconut water), using specially designed flasks and the rotating 'Steward' wheel. He unequivocally demonstrated that plant cells are totipotent, carrying the genetic information to enable them to develop into complete plants, often by embryogenesis, if given the right chemical stimuli in the correct order - thus vindicating an earlier prophecy that this would be so.

Professor F.C. Steward discovered and laid the foundation for plant tissue culture; genetic engineering and plant biotechnology of plants be they food crops or trees.

His most important scientific contribution came in 1958, when he established that plants could be totally regenerated from one cell. The finding revolutionized the world of plant cell biology, establishing for the first time that plant cuttings and shoots were no longer required to propagate hybrids and create mutations but that individual plant cells contained all the necessary information to regulate the entire plant organism. His discovery of the means to obtain such regeneration has formed the basis of the entire field of plant molecular biology, meaning that clones, hybrids and mutations of plants can be accomplished in the laboratory rather than having to resort to the far longer and cumbersome process of taking and then cultivating cuttings.

From his Cornell classrooms and laboratories, Steward was responsible for creating and inspiring a generation of botanists. Former students said that his lectures, in "advanced plant physiology" were the high point of their education. The lectures covered an entire year, he used no notes, and would speak as he walked back and forth in front of the lecture theater in Plant Science hall. From the outset of his career, Steward was often associated with scientific controversy and he often tended to be at its epicenter. He believed that one could be and maybe should be a "majority of one" if scientific convictions dictated it.

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