Structure
The crystal structures of HBGF1 has been solved, and found to be related to interleukin 1-beta; both families to have the same 12-stranded beta-sheet structure; the beta-sheets are arranged in 3 similar lobes around a central axis, 6 strands forming an anti-parallel beta-barrel. In general, the beta-sheets are well-preserved and the crystal structures superimpose in these areas. The intervening loops are less well-conserved - the loop between beta-strands 6 and 7 is slightly longer in interleukin-1 beta.
Read more about this topic: Fibroblast Growth Factor
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