Fat Embolism - Laboratory Tests

Laboratory Tests

Laboratory tests are mostly nonspecific: Serum lipase level increases in bone trauma - often misleading. Cytologic examination of urine, blood and sputum with Sudan or oil red O staining may detect fat globules that are either free or in macrophages. This test is not sensitive, however, and does not rule out fat embolism. Blood lipid level is not helpful for diagnosis because circulating fat levels do not correlate with the severity of the syndrome. Decreased hematocrit occurs within 24–48 hours and is attributed to intra-alveolar hemorrhage. Alteration in coagulation and thrombocytopenia. In summary, the diagnosis of FES may be difficult because, except for the petechiae, there are no pathognomonic signs.