Familial Mediterranean fever (FMF) is a hereditary inflammatory disorder. FMF is an autoinflammatory disease caused by mutations in MEFV, a gene which encodes a 781–amino acid protein denoted pyrin.
The disorder has been given various names including familial paroxysmal polyserositis, periodic peritonitis, recurrent polyserositis, benign paroxysmal peritonitis, periodic disease or periodic fever, Reimann periodic disease or Reimann's syndrome, Siegal-Cattan-Mamou disease, and Wolff periodic disease. Note that "periodic fever" can also refer to any of the Periodic fever syndromes.
Read more about Familial Mediterranean Fever: Epidemiology, Diagnosis, Pathophysiology, Genetics, Treatment, History
Famous quotes containing the words familial and/or fever:
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—Anne Taylor Fleming (20th century)
“When I was very young and the urge to be someplace was on me, I was assured by mature people that maturity would cure this itch. When years described me as mature, the remedy prescribed was middle age. In middle age I was assured that greater age would calm my fever and now that I am fifty-eight perhaps senility will do the job. Nothing has worked.... In other words, I don’t improve, in further words, once a bum always a bum. I fear the disease is incurable.”
—John Steinbeck (1902–1968)