Quality of Clinical Trials
Evidence-based medicine attempts to objectively evaluate the quality of clinical research by critically assessing techniques reported by researchers in their publications.
- Trial design considerations. High-quality studies have clearly defined eligibility criteria and have minimal missing data.
- Generalizability considerations. Studies may only be applicable to narrowly defined patient populations and may not be generalizable to other clinical contexts.
- Follow-up. Sufficient time for defined outcomes to occur can influence the study outcomes and the statistical power of a study to detect differences between a treatment and control arm.
- Power. A mathematical calculation can determine if the number of patients is sufficient to detect a difference between treatment arms. A negative study may reflect a lack of benefit, or simply a lack of sufficient quantities of patients to detect a difference.
Read more about this topic: Evidence-based Medicine
Famous quotes containing the words quality of, quality and/or trials:
“Working parents are often told that it is the quality of time, rather than the quantity of time one spends with children, that is significant. Unfortunately, good quality time is difficult to define, to measure, and to make happen on schedule.”
—Joyce Portner (20th century)
“Anybody who knows the difference between the kind of conversation you have walking in the woods and the kind of conversation you have between the segments of a show on Nickelodeon can tell you that quality time exists. Quality time is when you and your child are together and keenly aware of each other. You are enjoying the same thing at the same time, even if it is just being in a room or going for a drive in the car. You are somehow in tune, even while daring to be silent together.”
—Louise Lague (20th century)
“Misfortune is never mournful to the soul that accepts it; for such do always see that every cloud is an angel’s face. Every man deems that he has precisely the trials and temptations which are the hardest of all others for him to bear; but they are so, simply because they are the very ones he most needs.”
—Lydia M. Child (1802–1880)