Design
The devices contain a spring-loaded needle that exits the tip of the device (in some cases through a sterile membrane) and penetrates the recipient's skin, to deliver the medication via subcutaneous or intramuscular injection.
Epinephrine autoinjectors contain a pre-determined dose of epinephrine, usually between 300 μg and 500 μg of active ingredient at a concentration of 1:1000. They typically contain more medication than the amount needed for a single dose, but any extra amount is not intended for use and is inaccessible without destroying the device. Manufacturers have also made pediatric dosed versions available at 150 μg of active ingredient, and there is also a version which contains two individual doses (in case a repeated application is required) sold under the trade name Twinject.
On August 13th, 2012, the US FDA approved a new version of epinephrine auto-injector made by Intelliject and Sanofi called the Auvi-Q. It is rectangular in shape, 3.5 inches by 2 inches by 0.5 inch. It has a soundchip in it to give audio cues to a patient or caregiver to aid in the proper use of the device.
In most countries, epinephrine is a prescription drug, and therefore obtaining the device requires a prescription from a doctor. However, in some jurisdictions, epinephrine autoinjectors are an over-the-counter drug and may be purchased from a pharmacy counter.
Read more about this topic: Epinephrine Autoinjector
Famous quotes containing the word design:
“If I commit suicide, it will not be to destroy myself but to put myself back together again. Suicide will be for me only one means of violently reconquering myself, of brutally invading my being, of anticipating the unpredictable approaches of God. By suicide, I reintroduce my design in nature, I shall for the first time give things the shape of my will.”
—Antonin Artaud (1896–1948)
“You can make as good a design out of an American turkey as a Japanese out of his native stork.”
—For the State of Illinois, U.S. public relief program (1935-1943)
“To nourish children and raise them against odds is in any time, any place, more valuable than to fix bolts in cars or design nuclear weapons.”
—Marilyn French (20th century)