Epidermolytic Hyperkeratosis - Genetics

Genetics

It is possible to classify epidermolytic hyperkeratosis based upon palm and sole hyperkeratosis.

This is a dominant genetic condition caused by mutations in the genes encoding the proteins keratin 1 or keratin 10.

  • Keratin 1 is associated with the variants affecting the palms and soles.
  • Keratin 10 is associated with the variants in which these are unaffected.

Read more about this topic:  Epidermolytic Hyperkeratosis