Treatment
Recent research has focused on changing the mixture of keratins produced in the skin. There are 54 known keratin genes, 28 type I intermediate filament genes and 26 type II, which work as heterodimers. Many share substantial structural and functional similarity, but are specialized for different cell types or conditions under which they are normally produced. If a drug can shift the balance of production toward an intact keratin gene, symptoms can be reduced. For example, sulforaphane, a compound found in broccoli, was found to reduce blistering in a mouse model to the point where affected pups could not be identified visually, when injected into pregnant mice (5 µmol/day = 0.9 mg) and applied topically to newborns (1 µmol/day = 0.2 mg in jojoba oil).
The latest news on EB is that Prof Jayamini Seneviratne a dermatologist attached to Lady Ridgeway Hospital for Children Colombo 8, Sri Lanka announced that he found a novel treatment modality epidermolysis bullosa.
Read more about this topic: Epidermolysis Bullosa
Famous quotes containing the word treatment:
“Any important disease whose causality is murky, and for which treatment is ineffectual, tends to be awash in significance.”
—Susan Sontag (b. 1933)
“To me, nothing can be more important than giving children books, It’s better to be giving books to children than drug treatment to them when they’re 15 years old. Did it ever occur to anyone that if you put nice libraries in public schools you wouldn’t have to put them in prisons?”
—Fran Lebowitz (20th century)
“I am glad you agree with me as to the treatment of the mining riots. We shall crush out the lawbreakers if the courts and juries do not fail.”
—Rutherford Birchard Hayes (1822–1893)