Theories
Currently, there are two different theories on the information processing that occurs on enhancers:
- Enhanceosomes - rely on highly cooperative, coordinated action and can be disabled by single point mutations that move or remove the binding sites of individual proteins.
- Flexible billboards - less integrative, multiple proteins independently regulate gene expression and their sum is read in by the basal transcriptional machinery
Read more about this topic: Enhancer (genetics)
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“Our books of science, as they improve in accuracy, are in danger of losing the freshness and vigor and readiness to appreciate the real laws of Nature, which is a marked merit in the ofttimes false theories of the ancients.”
—Henry David Thoreau (18171862)
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—D.H. (David Herbert)