Selection Effective Size
In an idealised Wright-Fisher model, the fate of an allele, beginning at an intermediate frequency, is largely determined by selection if the selection coefficient s >> 1/N, and largely determined by neutral genetic drift if s << 1/N. In real populations, the cutoff value of s may depend instead on local recombination rates. This limit to selection in a real population may be captured in a toy Wright-Fisher simulation through the appropriate choice of Ne. Populations with different selection effective population sizes are predicted to evolve profoundly different genome architectures.
Read more about this topic: Effective Population Size
Famous quotes containing the words selection, effective and/or size:
“When you consider the radiance, that it does not withhold
itself but pours its abundance without selection into every
nook and cranny”
—Archie Randolph Ammons (b. 1926)
“Women, because of their colonial relationship to men, have to fight for their own independence. This fight for our own independence will lead to the growth and development of the revolutionary movement in this country. Only the independent woman can be truly effective in the larger revolutionary struggle.”
—Women’s Liberation Workshop, Students for a Democratic Society, Radical political/social activist organization. “Liberation of Women,” in New Left Notes (July 10, 1967)
“There are obvious places in which government can narrow the chasm between haves and have-nots. One is the public schools, which have been seen as the great leveler, the authentic melting pot. That, today, is nonsense. In his scathing study of the nation’s public school system entitled “Savage Inequalities,” Jonathan Kozol made manifest the truth: that we have a system that discriminates against the poor in everything from class size to curriculum.”
—Anna Quindlen (b. 1952)