Edward Murphy or Ed Murphy may refer to:
- Eddie Murphy (born 1961), actor and comedian
- Edward Murphy (New York politician) (1836–1911), U.S. senator from New York, and mayor of Troy, New York
- Ned Murphy (fl. 1880s), Irish sportsman
- Edward A. Murphy, Jr. (1918–1990), American aerospace engineer, namesake of "Murphy's Law"
- Edward Preston Murphy (1904–1958), U.S. federal judge
- Edward Murphy (Medal of Honor) (died 1924), U.S. Army private, Medal of Honor recipient for actions during the Indian Wars in 1869
- Edward F. Murphy (died 1908), U.S. Army corporal, Medal of Honor recipient for actions during the Indian Wars in 1879
- Edward Sullivan Murphy (1880–1945), Northern Irish politician
- Edward Murphy (rower) (born 1971), American rower
- Edward Murphy (politician) (1818–1895), Canadian senator
- Ed Murphy (soccer) (born 1930), Scottish-born soccer player, played for the U.S. national team, 1955–1969
- Ed Murphy (first baseman) (1918–1991), baseball player for the Philadelphia Phillies
- Ed Murphy (pitcher) (1877–1935), baseball player for the Philadelphia Phillies
- Ed Murphy (activist) (born 1945), American activist
- Ed Murphy (basketball coach) (born 1941), American college basketball coach
Famous quotes containing the word murphy:
“Narcotics have been systematically scapegoated and demonized. The idea that anyone can use drugs and escape a horrible fate is an anathema to these idiots. I predict that in the near future, right wingers will use drug hysteria as a pretext to set up an international police apparatus.”
—Gus Van Sant, U.S. screenwriter and director, and Dan Yost. Father Tom Murphy (William S. Burroughs)