Production
The shot of Edmond O'Brien running down Market Street (between 4th and 6th Streets) in San Francisco was a "stolen shot," taken without city permits, with some pedestrians visibly confused as O'Brien bumps into them. D.O.A. producer Harry Popkin owned the Million Dollar Theater at the southwest corner of Broadway and Third Street in downtown Los Angeles, directly across the street from the Bradbury Building, where O'Brien's character confronted his murderer. Director Rudolph Maté liberally used Broadway and the Bradbury Building during location shooting and included the Million Dollar Theater's blazing marquee in the background. The theater would later serve the same function when Ridley Scott filmed Blade Runner at the Bradbury Building. The Bradbury Building still exists at 304 South Broadway.
After "The End" and before the listing of the cast, a credit states the medical aspects of this film are based on scientific fact, and that "luminous toxin is a descriptive term for an actual poison."
The rhythm and blues/jazz band playing at the Fisherman's Club while O'Brien's glass is being spiked was filmed on a Los Angeles soundstage after principal photography was completed. According to Jim Dawson in his 1995 book Nervous Man Nervous: Big Jay McNeely and the Rise of the Honking Tenor Sax, the sweating tenor saxophone player was James Streeter, also known as James Von Streeter. Other band members were Shifty Henry (bass), Al "Cake" Wichard (drums), Ray LaRue (piano), and Teddy Buckner (trumpet). However, rather than use the live performance, the music director went back and rerecorded the soundtrack with a big band, not a quintet as seen in the film, led by saxophonist Maxwell Davis.
Read more about this topic: D.O.A. (1950 film)
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—Albert Camus (19131960)
“The heart of man ever finds a constant succession of passions, so that the destroying and pulling down of one proves generally to be nothing else but the production and the setting up of another.”
—François, Duc De La Rochefoucauld (16131680)