Variation Across Species
DNA polymerases have highly conserved structure, which means that their overall catalytic subunits vary, on a whole, very little from species to species. Conserved structures usually indicate important, irreplaceable functions of the cell, the maintenance of which provides evolutionary advantages. Based on sequence homology, DNA polymerases can be further subdivided into seven different families: A, B, C, D, X, Y, and RT.
Some viruses also encode special DNA polymerases, such as Hepatitis B virus DNA polymerase. These may selectively replicate viral DNA through a variety of mechanisms. Retroviruses encode an unusual DNA polymerase called reverse transcriptase, which is an RNA-dependent DNA polymerase (RdDp). It polymerizes DNA from a template of RNA.
Read more about this topic: DNA Polymerase
Famous quotes containing the word species:
“If there is a species which is more maltreated than children, then it must be their toys, which they handle in an incredibly off-hand manner.... Toys are thus the end point in that long chain in which all the conditions of despotic high-handedness are in play which enchain beings one to another, from one species to another—cruel divinities to their sacrificial victims, from masters to slaves, from adults to children, and from children to their objects.”
—Jean Baudrillard (b. 1929)