DNA Methyltransferase - Clinical Significance

Clinical Significance

Because of the epigenetic effects of the DNMT family, some DNMT inhibitors are under investigation for treatment of some cancers :

  • Vidaza (5-azacitidine) in a phase II trial for AML
  • Dacogen (decitabine) in phase III trials for AML and CML

Read more about this topic:  DNA Methyltransferase

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    “History is the interpretation of the significance that the past has for us.”
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