Displacement Chromatography - Discovery

Discovery

The advent of displacement chromatography can be attributed to Arne Tiselius, who in 1943 first classified the modes of chromatography as frontal, elution, and displacement. Displacement chromatography has since found a variety of applications from isolation of transuranic elements to biochemical entities. The technique was redeveloped by Csaba Horváth, who employed modern high-pressure columns and equipment. It has since found many applications, particularly in the realm of biological macromolecule purification.

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