Toxicology and Safety
In the United States, consumption of added 5'-ribonucleotides averages 4 mg per day, compared to 2 g per day of naturally occurring purines. A review of literature by an FDA committee found no evidence of carcinogenicity, teratogenicity, or adverse effects on reproduction.
In 2004, disodium inosinate was removed from the food additive list by Codex Alimentarius Commission (but it is still mentioned on the last (2009) codex alimentarius list).
Read more about this topic: Disodium Inosinate
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“There is no calamity which a great nation can invite which equals that which follows a supine submission to wrong and injustice and the consequent loss of national self-respect and honor, beneath which are shielded and defended a people’s safety and greatness.”
—Grover Cleveland (1837–1908)