Toxicology and Safety
In the United States, consumption of added 5'-ribonucleotides averages 4 mg per day, compared to 2 g per day of naturally occurring purines. A review of literature by an FDA committee found no evidence of carcinogenicity, teratogenicity, or adverse effects on reproduction.
In 2004, disodium inosinate was removed from the food additive list by Codex Alimentarius Commission (but it is still mentioned on the last (2009) codex alimentarius list).
Read more about this topic: Disodium Inosinate
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“The high sentiments always win in the end, the leaders who offer blood, toil, tears and sweat always get more out of their followers than those who offer safety and a good time. When it comes to the pinch, human beings are heroic.”
—George Orwell (1903–1950)