Structure
The dentate gyrus consists of three layers of neurons: molecular, granular, and polymorphic. The middle layer is most prominent and contains granule cells that project to the CA3 subfield of the hippocampus. These granule cells project mostly to interneurons, but also to pyramidal cells and are the principal excitatory neurons of the dentate gyrus. The major input to the dentate gyrus (the so-called perforant pathway) is from layer 2 of the entorhinal cortex, and the dentate gyrus receives no direct inputs from other cortical structures. The perforant pathway is divided into the medial perforant path and the lateral perforant path, generated, respectively, at the medial and lateral portions of the entorhinal cortex. The medial perforant path synapses onto the proximal dendritic area of the granule cells, whereas the lateral perforant path does so onto the distal dendrites of these same cells.
Read more about this topic: Dentate Gyrus
Famous quotes containing the word structure:
“Vashtar: So it’s finished. A structure to house one man and the greatest treasure of all time.
Senta: And a structure that will last for all time.
Vashtar: Only history will tell that.
Senta: Sire, will he not be remembered?
Vashtar: Yes, he’ll be remembered. The pyramid’ll keep his memory alive. In that he built better than he knew.”
—William Faulkner (1897–1962)
“Science is intimately integrated with the whole social structure and cultural tradition. They mutually support one other—only in certain types of society can science flourish, and conversely without a continuous and healthy development and application of science such a society cannot function properly.”
—Talcott Parsons (1902–1979)
“One theme links together these new proposals for family policy—the idea that the family is exceedingly durable. Changes in structure and function and individual roles are not to be confused with the collapse of the family. Families remain more important in the lives of children than other institutions. Family ties are stronger and more vital than many of us imagine in the perennial atmosphere of crisis surrounding the subject.”
—Joseph Featherstone (20th century)