Deletion (genetics) - Causes

Causes

Causes include the following:

  • Losses from translocation
  • Chromosomal crossovers within a chromosomal inversion
  • Unequal crossing over
  • Breaking without rejoining

For synapsis to occur between a chromosome with a large intercalary deficiency and a normal complete homolog, the unpaired region of the normal homolog must loop out of the linear structure into a deletion or compensation loop.

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